| 2004 | Oscar Academy Awards, USA | Best Actor in a Leading Role for: Cold Mountain (2003) |
| 2000 | Oscar Academy Awards, USA | Best Actor in a Supporting Role for: The Talented Mr. Ripley (1999) |
| 2000 | Saturn Award | Best Supporting Actor for: The Talented Mr. Ripley (1999) |
| 2004 | BAFTA Film Award | Best Performance by an Actor in a Leading Role for: Cold Mountain (2003) |
| 2005 | Critics Choice Award | Best Acting Ensemble for: Closer (2004/I) Shared with: Clive Owen Natalie Portman Julia Roberts |
| 2002 | CFCA Award | Best Supporting Actor for: Artificial Intelligence: AI (2001) |
| 2004 | Empire Award | Best British Actor for: Cold Mountain (2003) |
| 2003 | Empire Award | Best British Actor for: Road to Perdition (2002) |
| 2001 | Empire Award | Best British Actor for: The Talented Mr. Ripley (1999) |
| 2001 | Audience Award | Best Actor for: Enemy at the Gates (2001) |
| 2004 | Golden Globe | Best Performance by an Actor in a Motion Picture - Drama for: Cold Mountain (2003) |
| 2002 | Golden Globe | Best Performance by an Actor in a Supporting Role in a Motion Picture for: Artificial Intelligence: AI (2001) |
| 2000 | Golden Globe | Best Performance by an Actor in a Supporting Role in a Motion Picture for: The Talented Mr. Ripley (1999) |
| 2004 | Audience Award Irish Film and Television Awards | Best International Actor for: Cold Mountain (2003) |
| 2004 | ALFS Award London Critics Circle Film | British Actor of the Year for: Cold Mountain (2003) |
| 2003 | ALFS Award | British Supporting Actor of the Year for: Road to Perdition (2002) |
| 2001 | ALFS Award | British Supporting Actor of the Year for: The Talented Mr. Ripley (1999) |
| 2007 | MTV Movie Award | Best Kiss for: The Holiday (2006) Shared with: Cameron Diaz |
| 2005 | MTV Movie Award | Best Kiss for: Sky Captain and the World of Tomorrow (2004) Shared with: Gwyneth Paltrow |
| 2003 | MTV Movie Award | Best Trans-Atlantic Breakthrough Performer |
| 2000 | MTV Movie Award | Best Musical Performance for: The Talented Mr. Ripley (1999) Shared with: Matt Damon Fiorello For the song "Tu Vuo' Fa L'Americano". |
| 2007 | NRJ Ciné Award | Best Kiss (Meilleur baiser) for: The Holiday (2006) Shared with: Cameron Diaz |
| 2002 | OFCS Award | Best Supporting Actor for: Artificial Intelligence: AI (2001) |
| 2005 | People's Choice Award | Favorite Leading Man |
| 2003 | PFCS Award | Best Actor in a Supporting Role for: Road to Perdition (2002) |
| 2002 | PFCS Award | Best Actor in a Supporting Role for: Artificial Intelligence: AI (2001) |
| 2004 | Golden Satellite Award | Best Performance by an Actor in a Motion Picture, Drama for: Cold Mountain (2003) |
| 2000 | Golden Satellite Award | Best Performance by an Actor in a Supporting Role, Drama for: The Talented Mr. Ripley (1999) |
| 2005 | Actor | Outstanding Performance by a Cast in a Motion Picture for: The Aviator (2004) Shared with: Alan Alda Alec Baldwin Kate Beckinsale Cate Blanchett Leonardo DiCaprio Ian Holm Danny Huston John C. Reilly Gwen Stefani |
| 2000 | Teen Choice Award | Film - Choice Breakout Performance for: The Talented Mr. Ripley (1999) |
| 2005 | VES Award | Outstanding Performance by an Actor or Actress in a Visual Effects Film for: Sky Captain and the World of Tomorrow (2004) |