Osmosis Jones
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Peter Farrelly and Bobby Farrelly, the impish impresarios of gross-out comedy, take their body function-inspired humor to new extremes in this mixture of live action and animation. Bill Murray stars as Frank, a zoo worker suffering from the effects of an unknown malady he contracted after eating an egg contaminated with simian saliva. Unknown to Frank, the inside of his body is actually a city (the City of Frank) teeming with cellular life, where the mysterious illness he's fighting is an invading enemy that must be defeated at all costs. It's up to Osmosis Jones (voice of Chris Rock),… More
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© Warner Bros. Pictures
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Rotten Tomatoes Score: 55%

Critic Reviews from Rotten Tomatoes

"The plot's so much old rote, and the characters have all the personality of protoplasm; but the anthropomorphising of this microcosmic metropolis is wonderfully imaginative, and the dialogue decidedly spiffy."
‑ , Time Out
"The animated sequences in Osmosis Jones are funny and clever and thoroughly entertaining, with plenty of lively imagination on display in the transposition of a 1970s cop movie to the inner workings of the human body."
‑ Norman Wilner, Toronto Star
"Mostly animated PG film has gross-out humor, violence."
‑ Nell Minow, Common Sense Media
"It is funny, original, and even contains a genuine, good-natured theme."
‑ Steven Snyder, Zertinet Movies
"I'd advise attendees of this film to go on an empty stomach, but if you're willing to endure the Farrellys' warped sense of humor and Murray's scratching, squirting, gas-passing antics, Osmosis Jones offers some lighthearted fun."
‑ John R. McEwen, Film Quips Online
"Remains stubbornly one-dimensional."
‑ Bill Wyman, Salon.com
"A very clever, very gross, very funny spoof of the clichéd cop genre."
‑ Mark Rahner, Seattle Times
"I enjoyed it. It's a fun, dumb and gross comedy that kids will love."
‑ Felix Vasquez Jr., Cinema Crazed
"...the whole thing eventually becomes bogged down in its own plot."
‑ David Nusair, Reel Film Reviews
"The over-riding question with all comedies is 'Are there many laughs in it?' Luckily, the answer is yes - there are lots of great jokes, and not all of the scatological kind."
‑ Matthew Turner, ViewLondon
"It should have been placed in a hazardous waste container, encased in concrete and dumped into the Farrelly brothers' septic tank."
‑ Rita Kempley, Washington Post
"Isn't a movie so much as a health-class nutrition lecture."
‑ Wesley Morris, San Francisco Chronicle
"You'll probably find yourself laughing at Bill Murray farting. I did."
‑ Chris Gore, Film Threat
"The ideas are there, hints of genius, but no one ignites them."
‑ Kimberley Jones, Austin Chronicle
"The design of this colorful interior metropolis is both clever and biologically correct."
‑ Margaret A. McGurk, Cincinnati Enquirer
More reviews for Osmosis Jones on Rotten Tomatoes