The Demented follows six college friends as they meet up for a carefree weekend in a beautiful rural home. A terrorist missile attack in a nearby town infects much of the townspeople with a deadly virus that induces rabies-like symptoms...with devastating consequences. Ravenous and fast, the infected townspeople turn their sights on the vacation home where the friends are gathered...and are now barricaded. How long can they hide? Even with the infected "sleeping" in the streets, can they make their escape? If so, to what?