Miu Miu model Kirsten Dunst has been replaced by Johnny Depp's partner Vanessa Paradis.
French singer Vanessa will be photographed by Mert Alas and Marcus Pioggott for the autumn advertising campaign.
Miu Miu are yet to officially comment on the switch, but it has been claimed Kirsten's departure may be linked to her recent stint in Utah's Cirque Lodge rehabilitation clinic.
Since leaving the clinic, Kirsten has been seen with her rumoured new boyfriend Ryan Gosling.
Vanessa will be following in the footsteps of Lindsay Lohan, Maggie Gyllenhaal and Laetitia Casta, who have all fronted campaigns for the company.
Vanessa, 35, who has two children with actor Johnny, is believed to be planning to tie the knot with her long-term partner on June 14.
A source close to the couple said: "Vanessa recently told Johnny that she would love to have a wedding. Johnny loves Vanessa very much, and he said if that's what would make her happy, then he would marry her."